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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAV3
All Species:
20.61
Human Site:
S290
Identified Species:
41.21
UniProt:
Q9UKW4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKW4
NP_001073343.1
847
97776
S290
S
G
V
E
S
A
I
S
S
L
D
Y
I
S
K
Chimpanzee
Pan troglodytes
XP_001150955
788
91255
N261
E
C
S
Q
R
A
N
N
G
R
F
T
L
R
D
Rhesus Macaque
Macaca mulatta
XP_001083337
847
97793
S290
S
G
V
E
S
A
I
S
S
L
D
Y
I
S
K
Dog
Lupus familis
XP_537047
831
95340
S274
S
G
V
E
S
A
I
S
S
L
D
N
I
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0C8
847
97949
S290
S
G
V
E
S
A
I
S
N
L
D
Y
I
S
K
Rat
Rattus norvegicus
P54100
843
97935
K292
S
Q
V
E
S
A
I
K
H
L
D
Q
V
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505586
846
97900
N290
S
H
M
E
I
A
Q
N
T
L
N
H
L
I
A
Chicken
Gallus gallus
NP_996745
846
97797
S290
S
Q
V
E
T
A
I
S
C
L
D
N
I
S
K
Frog
Xenopus laevis
NP_001086991
845
97765
K294
S
Q
V
E
S
A
T
K
Y
L
E
K
T
S
M
Zebra Danio
Brachydanio rerio
NP_001119865
822
94769
S284
S
H
V
E
S
A
I
S
L
L
D
F
I
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NHV9
793
91337
E264
L
I
F
P
R
I
R
E
L
V
D
I
H
T
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q45FX5
1007
113536
K356
S
N
L
P
D
S
R
K
L
S
N
E
L
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.5
98.8
90.7
N.A.
95.4
59.5
N.A.
51.8
86.1
58
68.8
N.A.
30.8
N.A.
26.4
N.A.
Protein Similarity:
100
70.3
99.1
93.2
N.A.
97.1
75.5
N.A.
70.4
93.1
73
80.6
N.A.
50.7
N.A.
44.9
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
53.3
N.A.
26.6
73.3
46.6
73.3
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
66.6
N.A.
66.6
80
53.3
80
N.A.
26.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
84
0
0
0
0
0
0
0
9
9
% A
% Cys:
0
9
0
0
0
0
0
0
9
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
67
0
0
0
9
% D
% Glu:
9
0
0
75
0
0
0
9
0
0
9
9
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% F
% Gly:
0
34
0
0
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
17
0
0
0
0
0
0
9
0
0
9
9
0
0
% H
% Ile:
0
9
0
0
9
9
59
0
0
0
0
9
50
9
0
% I
% Lys:
0
0
0
0
0
0
0
25
0
0
0
9
0
0
67
% K
% Leu:
9
0
9
0
0
0
0
0
25
75
0
0
25
9
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
9
0
0
0
0
9
17
9
0
17
17
0
0
0
% N
% Pro:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
25
0
9
0
0
9
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
17
0
17
0
0
9
0
0
0
9
0
% R
% Ser:
84
0
9
0
59
9
0
50
25
9
0
0
0
50
0
% S
% Thr:
0
0
0
0
9
0
9
0
9
0
0
9
9
9
9
% T
% Val:
0
0
67
0
0
0
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _